alter 33

norwood 1 momentan

regimen 5.8.08-aktiv m shampoo jeden zweiten abend seit 11/07-----bockshornkleesamen 4bis5 esslöffel tägl.----salbeitee---thymiantee---b und c vitamine

abgesetzt   minox 10/07-6/08 nur flaumhaare ab und zu,oft schuppen und ausschläge-----minox+fin ebenso---minox+melantonin ebenso

wieder versuchende mittel demnächst    aloe vera---ingwer  beides topisch                                                           

update:ab anfang november 08 nun 1mal täglich follicare topical spray

update 25.12.08:sichtbare dunkle flaumhaare in den ghe .front und schläfen leicht ausgedünnt durch leichtes shedding des topical sprays,ausgefallende haare kommen langsam sichtbar wieder

Dies ist ein erster Beitrag um zu sehen, wie das Tagebuch funktioniert. Man kann fett, kursiv und noch vieles mehr

Background

Finasteride is a 5alpha-reductase inhibitor that has proved to be an effective treatment for men with androgenetic alopecia.

Objectives

To investigate the hormonal influence of finasteride 1 mg daily on hormonal levels and hair growth in men of different ages and with different degrees of alopecia according to the Hamilton-Norwood scale.

Methods

Two hundred and seventy men aged 14-58 years with male androgenetic alopecia III-VI Hamilton-Norwood score (II-III Ebling score) were treated with finasteride 1 mg daily. Steroid hormone (free testosterone, 5alpha-dihydrotestosterone, dehydroepiandrosterone-sulphate, delta4-androstenedione, 17-hydroxyprogesterone), prostate-specific antigen (PSA) and sebum levels, and trichogram changes were determined at baseline, and at 6 and 12 months of treatment.

Results

According to significant hormonal statistical analysis, the patients were divided by age (up to or over 26 years). In the group of patients </= 26 years, higher levels of 5alpha-dihydrotestosterone were found at the beginning of the treatment, but there was a 50% decrease between the onset of treatment and month 12, particularly noticeable at 6 months (P < 0.05) of treatment, running parallel to an improvement of the alopecia and an increase of anagen hairs in the trichogram. At 1 year, PSA levels decreased 20%, particularly in patients > 26 years. No variations in sebum levels were observed.

Conclusions

High levels of 5alpha-dihydrotestosterone in patients </= 26 years at the beginning of treatment are a predictive factor of good response to treatment with finasteride 1 mg daily.

Camacho FM; García-Hernández MJ; Fernández-Crehuet JL: Value of hormonal levels in patients with male androgenetic alopecia treated with finasteride: better response in patients under 26 years old

The British journal of dermatology; VOL: 158 (5); p. 1121-4 /200805/